A New Tool for Men’s Testosterone & Fertility: Opioid Antagonists

3 months ago
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Citations:
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Petraglia, F., Vale, W., & Rivier, C. (1986). BETA-ENDORPHIN MODULATES THE INHIBITORY ACTION OF CORTICOTROPIN-RELEASING FACTOR ON LUTEINIZINC HORMONE SECRETION. Progress in Opioid Research, 331. https://books.google.com/books?hl=en&lr=&id=1KqJllN9ghQC&oi=fnd&pg=PA331&dq=Petraglia,+F.,+Value,+WITH.,+%26+Rivier,+C.+(1986).+BETA-ENDORPHIN+MODULATES+THE+INHIBITORY+ACTION+OF+CORTICOTROPIN-RELEASING+FACTOR+ON+LUTEINIZING+HORMONE+SECRETION.%C2%A0Progress+in+Opioid+Research,+331.&ots=Bd2uV04s8C&sig=_0-5K5a_H702kOm0bWK0QBYJTkM#v=onepage&q&f=false

Wiesner JB, Koenig JI, Krulich L, Moss RL 1984 Site of action for -endorphin-induced changes in plasma luteinizing hormone and prolactin in the ovariectomized rat
https://www.sciencedirect.com/science/article/abs/pii/0024320584900614

Pimpinelli, F., Parenti, M., Guzzi, F., Piva, F., Hokfelt, T., & Maggi, R. (2006). Presence of delta opioid receptors on a subset of hypothalamic gonadotropin releasing hormone (GnRH) neurons. Brain research, 1070(1), 15-23. https://www.sciencedirect.com/science/article/abs/pii/S0006899305015453

Weems, P. W., Coolen, L. M., Hileman, S. M., Hardy, S., McCosh, R. B., Goodman, R. L., & Lehman, M. N. (2018). Evidence that dynorphin acts upon KNDy and GnRH neurons during GnRH pulse termination in the ewe. Endocrinology, 159(9), 3187-3199. https://academic.oup.com/endo/article-abstract/159/9/3187/5053743

MOSTARI, M. P., Ieda, N., Deura, C., Minabe, S., Yamada, S., Uenoyama, Y., ... & Tsukamura, H. (2013). Dynorphin-kappa opioid receptor signaling partly mediates estrogen negative feedback effect on LH pulses in female rats. Journal of Reproduction and Development, 59(3), 266-272. https://www.jstage.jst.go.jp/article/jrd/59/3/59_2012-193/_article/-char/ja/

Agirregoitia, E., Valdivia, A., Carracedo, A., Casis, L., Gil, J., Subiran, N., ... & Irazusta, J. (2006). Expression and localization of δ-, κ-, and μ-opioid receptors in human spermatozoa and implications for sperm motility. The Journal of Clinical Endocrinology & Metabolism, 91(12), 4969-4975.https://academic.oup.com/jcem/article-abstract/91/12/4969/2656533

Tenhola, H., Sinclair, D., Alho, H., & Lahti, T. (2012). Effect of opioid antagonists on sex hormone secretion. Journal of endocrinological investigation, 35(2), 227-230. https://link.springer.com/article/10.3275/8181

Li, X. F., Knox, A. M. I., & O'byrne, K. T. (2010). Corticotrophin-releasing factor and stress-induced inhibition of the gonadotrophin-releasing hormone pulse generator in the female. Brain research, 1364, 153-163. https://www.sciencedirect.com/science/article/abs/pii/S0006899310018184

Veldhuis, J. D., Rogol, A. D., Samojlik, E., & Ertel, N. H. (1984). Role of endogenous opiates in the expression of negative feedback actions of androgen and estrogen on pulsatile properties of luteinizing hormone secretion in man. The Journal of clinical investigation, 74(1), 47-55. https://www.jci.org/articles/view/111417

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#pct #fertility #testosterone

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