Brain Food or Foe? The Dual Faces of Vitamin B1

Thiamine sweet spot seems to be 0.68 mg/day among healthy older people to ward off decline. Optimal maintenance dose seems to be 0.6 to less than 1 mg/day.

There seems to be a J-shaped curve between dietary thiamine (vitamin B1) and worsening mental acuity among cognitively healthy older people, suggests research published in the open access journal General Psychiatry.

The sweet spot seems to be a daily intake of 0.68 mg, below which there is relatively little impact. But higher daily intake was strongly associated with cognitive decline, with the optimal maintenance dose 0.6 to less than 1 mg/day, the findings show.