The Science and Clinical Approaches to Aging - Dr. Ahvie Herskowitz (Nov 2019)

Dec 19, 2019
"The Science and Clinical Approaches to Aging" is presented by Dr. Ahvie Herskowitz, MD at the November 21 , 2019 meeting of the Silicon Valley Health Institute in Palo Alto, CA.

Only 1 in 5,000 Americans live past 100 years. In few small communities around the globe, this number can reach as high as 1 in 10. Children of centenarians are also more likely to live to 100 years, so we know that there is, at least a genetic component, although healthy epigenetic influences in the long-lived communities include advanced social structure, good nutrition, lots of exercise and usually red wine!

A fundamental truth is that centenarians ultimately die from the same degenerative disorders that we die from, only 25 years later. They also manifest the first signs of chronic degenerative diseases (osteoarthritis, cardiovascular, cerebrovascular and renal disease) much later in life, into their 90’s.

To summarize my own 10-year journey to understand the molecular mechanisms of why we age and how to prevent age-related physical and mental decline, I will begin with a description of the gene clusters that are found in centenarians. These gene clusters offer significant insights into how a small human subpopulation has the ability to stay in repair mode much longer and more efficiently than those without these gene clusters.

About Dr. Ahvie Herskowitz, MD
Dr. Herskowitz’s extensive training includes a medical degree from The Albert Einstein College of Medicine, residencies in Anatomic Pathology and Internal Medicine, and Fellowship training in Cardiology at The Johns Hopkins Medical Center. During his 12 years at Johns Hopkins, he became Associate Professor of Medicine and Immunology and Molecular Microbiology and led a research team in the study of molecular and immunological mechanisms of inflammation, autoimmunity, ischemia, heart transplantation rejection and congestive heart failure.

Over the past 15 years, he helped establish and lead innovative health care non-profit research and development organizations that have domestic and worldwide social impact. He was head of a 75-person research team at the Ischemia Research and Education Foundation, working with over 100 leading heart surgery hospitals around the world, reducing adverse outcomes during and after heart surgery. Since 1999, he has been Clinical Professor of Medicine at University of California at San Francisco, and Co-founder and Chief Medical Officer of the Institute for OneWorld Health, the first non-profit pharmaceutical company in the United States. He is President of the American College for Advancement in Medicine (ACAM), one of the most respected Integrative Medicine societies in the US; Chairman of the Board of Directors for iRND3, an organization that discovers new medicines for rare and neglected diseases, and serves on the Board for PVRI, Pulmonary Vascular Research Institute.

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