The Next 500 Years Of Space Colonization

Less than a century has passed since the first time a human arrived in space until today. During that time, space science and technology have advanced by leaps and bounds, and we have managed to take humans to the moon, robots to other planets, and even spacecraft to the ends of the solar system.
If we have achieved all this in less than 80 years, what will we achieve in the next 200 years or 500?
Will there be human bases on the moon, or will we finally begin to populate Mars?
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