HMB and Alzheimer’s disease Show 1151 AUG 2023

“This may be one of the safest and the easiest approaches to halt disease progression and protect memory in Alzheimer’s disease patients,” said Kalipada Pahan, PhD, the Floyd A. Davis, MD, Professor of Neurology and professor of neurological sciences, biochemistry and pharmacology at RUSH Medical College.

#hmb #alzheimers #cognition

Ramesh K. Paidi, Sumita Raha, Avik Roy, Kalipada Pahan. Muscle-building supplement β-hydroxy β-methylbutyrate binds to PPARα to improve hippocampal functions in mice. Cell Reports, 2023; 112717 DOI: 10.1016/j.celrep.2023.112717

β-hydroxy β-methylbutyrate, hmb, mild cognitive impairment, ppar, plaque, tangles, neuroprotective, fatty acids, blood brain barrier, peroxisome proliferator-activated receptor, memory, morphological plasticity, hippocampal neurons