Super Agers: From Their Cells to Their Psychology, They Show Us How to Live to 100 and Beyond

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Super agers—from their cellular makeup to their daily habits and states of mind—are living studies in what it takes to live longer and healthier.
Biologically, they preserve better gray matter volume in their brains. Behaviorally, they tend to exercise, eat well, and avoid smoking and drinking to excess.
But what, at a deeper level, defines the formula for living the longest life possible?
Dr. Dayan Goodenowe identifies how we adapt to our changing environments—from the cellular to the behavioral level—as the prime determinant of how well we age.
Dr. Goodenowe has spent decades researching the biochemistry of neurological disorders, including Alzheimer’s disease, ALS, and autism.
How well we adapt, he says, comes down to the interplay between our purpose and our function. And this dynamic is inherent at all levels of our being. For example, at the societal level, a person adapts the teaching skills required to fulfill the purpose of being a teacher; at the cellular level, a cell adapts the motor-neuron function required to fulfill the purpose of moving our feet.
However, in the example of motor-neuron disease (amyotrophic lateral sclerosis—ALS) this interplay is compromised by a lack of “raw material” to maintain the function of foot movement.
The “raw materials” are the requisite nutrients, says Dr. Goodenowe.
As such, restoring function to patients suffering from or at risk of developing ALS, Alzheimer’s disease, and other neurological disorders is a matter of supplying the materials—in the form of targeted nutrition—that are needed.
On Vital Signs with Brendon Fallon, Dr. Goodenowe reveals changes in his own brain over 18 months of targeted nutrition—changes that challenge the idea that brain health and function are destined to decline with age.
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