Ivermectin's Anti-Cancer Mechanisms

First, let’s quickly summarize the anti-cancer mechanisms (a quick summary can be found in 2022 paper by Loftalizadeh et al):
"Ivermectin induces tumor cell death: apoptosis, autophagy, pyroptosis
Ivermectin inhibits tumor initiation and tumor progression (via WNT inhibition, YAP1 inhibition)
Ivermectin inhibits tumor growth and proliferation (via Akt/mTOR inhibition, MAPK inhibition)
Ivermectin stops cancer cell migration, invasion and metastasis (via PAK1 inhibition - seen in 70% of all cancers, EMT inhibition, RNA Helicase inhibition)
Ivermectin causes cancer cell mitochondrial dysfunction (inhibits mitochondrial biogenesis, increases reactive oxygen species selectively only in cancer cells)
Ivermectin regulates tumor microenvironment (to inhibit tumor growth and progression, via P2X7 path, ICD - mediates immunogenic cell death)"
https://vigilantnews.com/post/can-ivermectin-treat-turbo-cancers-9-ivermectin-papers-reviewedShow more

Why mRNA really got Nobel Prize (Dr. Robert Malone)
https://www.science.org/content/article/mrna-discovery-paved-way-covid-19-vaccines-wins-nobel-prize-physiology-medicine
Aside from honoring a discovery that opened a new research avenue, the Nobel Prize might have a practical impact on uptake of COVID-19 vaccines, suggests Olle Kämpe, vice chair of the committee that chose the winners of this year’s award. Although Kämpe believes it’s unlikely that people who are firmly against vaccines will have second thoughts, he expects “giving a Nobel Prize for this COVID-19 vaccine can make hesitant people take the vaccine and be sure that it’s very efficient and it’s safe.”

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