Factors behind female sex bias in Hidradenitis Suppurativa

#hidradenitissuppurativa #dermaimmunology
Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition ( abscesses, sinus tracts, & scarring) in the intertriginous areas. Hidradenitis suppurativa (HS) has a prevalence among females(female-to-male 3:1. The female sex bias in HS is likely a result of multiple factors, including hormones, genetics, environmental factors, & the microbiome.
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References:
https://onlinelibrary.wiley.com/doi/10.1111/exd.14155
Key moments"
00:00 Introduction
03:36 Intrinsic factors
04:56 Intrinsic factors, Hormones
11:45 Intrinsic factors, X chromosome dosage
15:16 Intrinsic factors, Other sex-biased genes
16:45 Extrinsic Factors, Microbiome
19:45 Extrinsic Factors, Smoking
22:25 Conclusion
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