How Do Erectile Dysfunction Drugs Work? A Complete Rundown on PDE5 Inhibitors
If you’ve searched online for information about treating ED, you’ve likely heard of medications called PDE5 inhibitors.
PDE5 inhibitors are medications that improve blood flow to certain tissues, including the tissue of the penis. They work by inhibiting the action of phosphodiesterase-5, an enzyme that can be found in the smooth muscle cells of blood vessels.
Although PDE5 inhibitors were originally designed to treat cardiovascular health issues, they’re most commonly used today to treat erectile dysfunction.
Common PDE5 inhibitors available today include Viagra® (which contains the active ingredient sildenafil), Cialis® (tadalafil), Levitra® (vardenafil) and Stendra® (avanafil).
Below, we’ve explained what PDE5 inhibitors are, how they work and how you might be able to use them to treat ED.
We’ve also discussed several important topics related to PDE5 inhibitors, from side effects and interactions to frequently asked questions and more.
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