Serotonin: does it make you Happy, Narcissistic or....? Feel Good Biochemistry Part 2 | Episode 14

In this Episode which became Part 2 in our 'Adjusting Hormones and Neurochemicals to Feel Happy' Series, we discuss Serotonin: Is it really the key to happiness and relaxation, or a stress chemical which can make you feel suicidal or narcissistic? What is Serotonin Syndrome?

We explore the options, reflecting on Ray Peat's research into the area of which chemicals keep us young and happy and which ones make us stressed and age prematurely, as well as the potential implications to a spiritual or religious practice.

We end with a review of everything we've covered so far, and how it ties into the Polyvagal theory, as we explore which hormones and chemicals may be responsible for creating the Ventral Vagal, Sympathetic, and Dorsal Vagal Modes of the Central Nervous System, how we can end up feeling bad most of the time, and the best path back to feeling good most of the time.

References from this episode:

RP - Feel Good 1 - https://youtu.be/L3qmdDp6RxA
RP - Metabolism - https://youtu.be/y1kZFAqbbm0
RP - Digestion - https://youtu.be/clP5VBqOUfE
RP - Stress & Anxiety - https://youtu.be/xApOAM30SpA
RP - Thyroid - https://youtu.be/D-uBXy3StYY

The High Serotonin Personality
https://men-elite.com/2019/01/17/the-high-serotonin-personality/
Serotonin inhibition of the NMDA receptor/nitric oxide/cyclic GMP pathway in human neocortex slices: involvement of 5-HT2C and 5-HT1A receptors

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1572268/

Serotonin-prefrontal cortical circuitry in anxiety and depression phenotypes: pivotal role of pre- and post-synaptic 5-HT1A receptor expression
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047678/

Serotonin and decision making processes
https://www.sciencedirect.com/science/article/abs/pii/S0149763411001114

Serotonin The Fraudulent Antidepressant
https://men-elite.com/2020/04/24/serotonin-the-fraudulent-anti-depressant/
Investigating the Molecular Basis of Major Depressive Disorder Etiology
https://nyaspubs.onlinelibrary.wiley.com/doi/10.1196/annals.1410.018

Serotonergic Systems, Anxiety, and Affective Disorder
https://nyaspubs.onlinelibrary.wiley.com/doi/abs/10.1196/annals.1410.004

Metabolic, Molecular, and Behavioral Effects of Western Diet in Serotonin Transporter-Deficient Mice: Rescue by Heterozygosity?
https://pubmed.ncbi.nlm.nih.gov/32132889/

Serotonin and Sleep: Molecular, Functional, and Clinical Aspects
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675905/

Parasite Rex
https://www.amazon.com/Parasite-Rex-Bizarre-Dangerous-Creatures/dp/074320011X

Sadh Guru - Inner Engineering
https://innerengineering.sadhguru.org/online-program

Ray Peat - https://raypeat.com/articles/articles/serotonin-depression-aggression.shtml

You can find Elwin’s recommended Feeling Good Supplements here:
https://feelyounger.net/collections/mood-support

And remember to use code “REJUVENATEME” to tell them we sent you and to get 20% OFF your first order.

If you’d like to know which Genetic Factors are influencing your Happiness, go to
https://geneticinsights.co/happy

And use promo code “REJUVENATE” to tell Genetic Insights we sent you and get 20% OFF your first order.

You can follow Elwin on Twitter @therealelwin

And you can find Krissy on Twitter @KrissyHawkes

Timestamps/Annotations

00:00:00 Feeling Good Part 2 Rejuvenate Podcast
00:02:15 Elwins’ deep dive into serotonin
00:19:30 Learned helplessness
00:26:12 Serotonin Receptors and their actions
00:34:40 Anti-stress and stress chemicals (Ray Peat Theory)
00:46:08 Serotonin and gut dysbiosis
00:54:25 Serotonin and status
01:00:11 How to lower serotonin naturally
01:12:19 Is desire the cause of suffering
01:22:58 Poly vagal theory - The downward spiral
01:35:11 Identify where you are at and how to fix it
01:56:58 Final thoughts

Disclaimer:

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Original Music Composed and Performed by @ChesneyHawkes https://chesneyhawkes.com/

Executive Producer - Chad Newman