Ozempic and Weight Loss - Pharmacist Explains

In my last video I explained what Ozempic is and how it works. Today I go through the claims regarding weight loss and see what the evidence says. With everyone hopping onto social media to talk about how amazing Ozempic is for weight loss, I thought I would give a simple and realistic review of what the research currently says and weigh in on the topic.

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Research articles used:

1. Once-Weekly Semaglutide in Adults with Overweight or Obesity
https://www.nejm.org/doi/full/10.1056/NEJMoa2032183

2. Weight Loss Outcomes Associated With Semaglutide Treatment for Patients With Overweight or Obesity
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2796491

3. Efficacy and safety of semaglutide on weight loss in obese or overweight patients without diabetes: A systematic review and meta-analysis of randomized controlled trials
https://pubmed.ncbi.nlm.nih.gov/36188627/

4. Two-year effects of semaglutide in adults with overweight or obesity: the STEP 5 trial
https://www.nature.com/articles/s41591-022-02026-4

5. Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension
https://pubmed.ncbi.nlm.nih.gov/35441470/

0:00 Intro
0:55 Review of how Ozempic can reduce weight
1:15 What does the research say?
3:27 What happens when you stop taking Ozempic?
5:30 Nutritional concerns about Ozempic
6:20 Wrap up