Jacksonville Jaguars vs Indianapolis Colts Week 1 Prediction, Picks & Best Bets | NFL Betting Advice

🏈 The Jaguars shocked the league last season winning their division, and this year they'll open up against the Indianapolis Colts. These AFC South rivals will battle in Week 1, and Rob Veno joins WagerTalk Today to give early betting advice for this Jags-Colt clash. The Jaguars are currently listed as 3.5-point road favorites over two months out.

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