New Research: How Creatine, as a Nootropic, can Enhance Your Healthspan

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2 years ago
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today I will be looking at creatine, but not for its muscle building benefits, but to look at 20+ studies which looked into its Nootropic benefits.
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Links:
https://link.springer.com/article/10.1007/s40279-023-01870-9
Wyss, M., & Kaddurah-Daouk, R. (2000). Creatine and creatinine metabolism. Physiological reviews, 80(3), 1107-1213.
Kreider, R. B., & Stout, J. R. (2021). Creatine in health and disease. Nutrients, 13(2), 447.
Smith-Ryan, A. E., Cabre, H. E., Eckerson, J. M., & Candow, D. G. (2021). Creatine supplementation in women’s health: a lifespan perspective. Nutrients, 13(3), 877.
Candow, D. G., Forbes, S. C., Chilibeck, P. D., Cornish, S. M., Antonio, J., & Kreider, R. B. (2019). Effectiveness of creatine supplementation on aging muscle and bone: focus on falls prevention and inflammation. Journal of clinical medicine, 8(4), 488.
Syrotuik, D. G., & Bell, G. J. (2004). Acute creatine monohydrate supplementation: a descriptive physiological profile of responders vs. nonresponders. The Journal of Strength & Conditioning Research, 18(3), 610-617.
Forbes, S. C., Cordingley, D. M., Cornish, S. M., Gualano, B., Roschel, H., Ostojic, S. M., … & Candow, D. G. (2022). Effects of creatine supplementation on brain function and health. Nutrients, 14(5), 921.
Fons, C., & Campistol, J. (2016, November). Creatine defects and central nervous system. In Seminars in pediatric neurology (Vol. 23, No. 4, pp. 285-289). WB Saunders.
Braissant, O., & Henry, H. (2008). AGAT, GAMT and SLC6A8 distribution in the central nervous system, in relation to creatine deficiency syndromes: a review. Journal of inherited metabolic disease, 31, 230-239.
Bender, A., & Klopstock, T. (2016). Creatine for neuroprotection in neurodegenerative disease: end of story?. Amino Acids, 48, 1929-1940.
[10] Christie, D. L. (2007). Functional insights into the creatine transporter. Subcellular Biochemistry, 46, 99.
Ostojic, S. M., Stojanovic, M., Drid, P., Hoffman, J. R., Sekulic, D., & Zenic, N. (2016). Supplementation with guanidinoacetic acid in women with chronic fatigue syndrome. Nutrients, 8(2), 72.
Rawson, E. S., Lieberman, H. R., Walsh, T. M., Zuber, S. M., Harhart, J. M., & Matthews, T. C. (2008). Creatine supplementation does not improve cognitive function in young adults. Physiology & behavior, 95(1-2), 130-134.
McMorris, T., Mielcarz, G., Harris, R. C., Swain, J. P., & Howard, A. (2007). Creatine supplementation and cognitive performance in elderly individuals. Aging, Neuropsychology, and Cognition, 14(5), 517-528.
Watanabe, A., Kato, N., & Kato, T. (2002). Effects of creatine on mental fatigue and cerebral hemoglobin oxygenation. Neuroscience research, 42(4), 279-285
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