Premium Only Content

How “Ozempic” Works – Weight Loss, Weight Regain, & Neuroscience | Nick Sterling, MD, PhD #7
How do drugs like Ozempic (semaglutide) cause weight loss? What happens when someone comes off of these drugs? In this episode, we discuss how these drugs (GLP-1 receptor agonists) target specific areas in the brain to suppress appetite and facilitate weight loss. We also discuss clinical trials data suggesting that these drugs and/or the weight loss that they facilitate may have cardioprotective effects. Lastly, we will also examine evidence regarding weight regain when coming off of these drugs and common side effects.
Link to episode on neuroscience of appetite regulation:
https://www.youtube.com/watch?v=i3RzV9vS_FA
#healthspan, #semaglutide, #ozempic, #wegovy, #science, #weightloss
Chapters:
00:00 - Intro
01:31 - What Does GLP-1 Do?
02:08 - GLP-1 Receptors in the Brain
02:52 - Activating the GLP-1 "Switch" (Receptors)
04:13 - Clinical Trials - Semaglutide for Weight Loss
05:29 - Semaglutide and Heart & Metabolic Health
05:54 - For How Long Does Semaglutide Work?
06:35 - Weight Regain After Stopping Semaglutide
08:24 - Side Effects of GLP-1 Receptor Agonists
09:37 - Take-Home Points
10:20 - Outro
Social & Website:
Instagram - https://www.instagram.com/sterlingmdphd
Twitter - https://twitter.com/sterlingmdphd
Facebook - https://www.facebook.com/sterlingmdphd
TikTok - https://www.tiktok.com/@sterlingmdphd
Newsletter - http://eepurl.com/hQpdqT
Subscribe to the Podcast:
Apple Podcasts: https://apple.co/3y438C9
Spotify: https://open.spotify.com/show/5TDUK3F2sJXfnG63hSxJhT?si=40bb52e5b53f404c
Google Podcasts: https://bit.ly/3Olanei
References & Show Notes:
http://www.nicksterling.com/
The content of this video is for general information purposes only and does not constitute the practice of medicine or any other healthcare professional services. The content of this video is not medical advice. No doctor-patient relationship is formed. The content of this podcast should not take precedence over information provided to you by your healthcare provider or official public health sources. Please visit nicksterling.com/terms for full Terms of Use.
-
1:24:06
JULIE GREEN MINISTRIES
2 hours agoLIVE WITH JULIE
72.6K133 -
LIVE
PudgeTV
3 hours ago🟠 Witcher 3: The Wild Hunt Day 11 | Where TF is Ciri?
58 watching -
LIVE
The Pete Santilli Show
3 days agoBREAKING: New Document Dump Proves Obama & Clinton Conspiracy To Frame President Trump! [EP4641-8AM]
991 watching -
LIVE
Welcome to the Rebellion Podcast
12 hours ago $0.75 earnedOh Obama - WTTR Podcast Live 7/21
161 watching -
LIVE
The Bubba Army
2 days agoShannon Sharpe Settles Rape Lawsuit - Bubba the Love Sponge® Show | 7/21/25
1,680 watching -
16:07
Clownfish TV
4 hours agoAstronomer CEO 'Resigns' After Coldplay Kiss Cam Becomes a Meme!
17.8K10 -
32:32
Ohio State Football and Recruiting at Buckeye Huddle
16 hours agoOhio State Football: The 10 Best Players of the Ryan Day Era
21.6K -
15:45
Professor Gerdes Explains 🇺🇦
1 day agoThe Two-Front War Nobody's Ready For - NATO Commander Breaks It Down
16K2 -
2:03:51
BEK TV
2 hours agoTrent Loos in the Morning 7/21/2025
16.9K -
39:31
Athlete & Artist Show
19 hours ago $2.38 earnedBaby Boychuk Is BORN, Playing With Nick Tarnasky In The WHL
29K4