Monkeypox Drug and Vaccine Discovery

For a new viral disease to emerge, the causative virus must infect and successfully invade its host, bypassing the complex and sophisticated antiviral defenses that have evolved in all animals. Three major steps have been distinguished in the processes of viral disease emergence or re-emergence: (1) introduction of a viral pathogen into a new host species, (2) establishment of the pathogen in the new host, and (3) dissemination of the pathogen among a large number of individuals of the new host species to bring about outbreaks, epidemics or pandemics.
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