1960s, the use of thalidomide by women pregnant or who subsequently became pregnant resulted,'

"In the late 1950s and early
1960s, the use of thalidomide in 46 countries
by women who were pregnant or who
subsequently became pregnant resulted in the
'biggest man-made medical disaster ever,' with
more than 10,000 children born with a range of
severe deformities, such as phocomelia, as well
as thousands of miscarriages."