Premium Only Content

The Evolution of Antibiotic Resistance in Gut Bacteria: Sharmily Khanam Explains Her Research
While scientists know antibiotic resistance is linked to the widespread use of antibiotics, understanding the physiology and microbiome of guts that have never been exposed to synthetic antibiotics might offer information to help address this resistance.
Researcher Sharmily Khanam designed a study to tackle this gap in knowledge. She explains
1. How our understanding of resistance mostly comes from clinicallybrelevant bacteria that's pathogenic and our understanding is therefore incomplete;
2. Where she found a population without any exposure to synthetic antibiotics and what her research process is; and
3. What pattern and discovery this research has offered, namely the ubiquitous nature of the antibiotic resistant gene and additional questions this raises.
Dr. Sharmily S. Khanam is a Postdoctoral Research Associate with the Department of Microbiology and Plant Biology at the University of Oklahoma. She explains her initial question in her research, namely what the microbial population in our ancestors was like and how resistant they were to the current antibiotics. She and her colleagues are therefore studying a population in a remote village in the Amazon Forest in Peru.
Currently they are studying the scope and extent of antibiotic resistance in the gut microbiome population of this ancestral-like population, comparing them with the gut microbial population, physiology, and antibiotic resistant population in the microbiome of people exposed to modern antibiotics.
They are trying to see if our ancestral microbiome was well positioned to tolerate the modern day antibiotics. She explains that researchers need to fill the gap of knowledge in understanding the molecular mechanism involved in resistance to a diverse group of antibiotics.
She adds that at the same time, this will provide a foundation to investigate and characterize the molecular mechanism in the bacterial population and how that is related to host metabolism—the combination of host and microbial population is creating the outcome that scientists need to understand in order to interrupt this process and prevent resistance. She adds an explanation of their findings thus far and explains how this may help the medical community.
To learn more about this study, see her LinkedIn profile and Google scholar account.
-
34:21
FGP
3 days agoMaster Antioxidant, Major Impact: How Glutathione Could Change Your Health Forever
441 -
LIVE
TimcastIRL
17 minutes agoBREAKING: Trump DOJ FIRES Epstein Prosecutor, James Comey's Daughter Amid Controversy | Timcast IRL
21,005 watching -
LIVE
Glenn Greenwald
3 hours agoCongress Again Dictates Curriculum & Faculty at Private Universities; How UnitedHealth Group Silences its Critics: With NYT Reporter David Enrich | SYSTEM UPDATE #488
7,438 watching -
LIVE
Barry Cunningham
1 hour agoPRESIDENT TRUMP IS BUILDING A NEW MAGA! ARE YOU READY FOR THE NEXT ACT?
2,479 watching -
LIVE
Dr Disrespect
8 hours ago🔴LIVE - DR DISRESPECT - STREAMING UNTIL WE GET 10 WINS
2,060 watching -
LIVE
RiftTV
2 hours agoCON INC: We Should All Just FORGET About Epstein | The Rift | Dinesh D’Souza, Lauren Witzke + More
614 watching -
LIVE
LIVE WITH CHRIS'WORLD
1 hour agoLIVE WITH CHRIS’WORLD - I Have So Many Questions Right Now
47 watching -
58:21
BonginoReport
3 hours agoTrump Deepens MAGA’s Epstein Divide - Nightly Scroll w/ Hayley Caronia (Ep.91) - 07/16/2025
110K58 -
LIVE
RalliedLIVE
5 hours ago $0.85 earned10 WINS WITH THE SHOTTY BOYS
84 watching -
LIVE
Playback Request Live
1 hour agoLevel Up: Our First Live Performance ft. Lady Desiree
120 watching