Premium Only Content

Hepatitis E virus in donation candidates and blood donors in Northeast Brazil. #HEV #Brazil #Blood
Abstract #HEV #Brazil #Blood
Oral transmission is the main route of hepatitis E virus (HEV) infection; however, genotypes 3 and 4 may also be transmitted by blood transfusion. Individuals who need blood products are often immunosuppressed, which increase the risk of severe disease and death by HEV. Despite this, blood banks in Brazil do not screen for HEV and epidemiological studies in this population are rare; this is an important issue as HEV-3 is frequently identified in the country. Herein, we analyzed the seroprevalence and risk factors for HEV seropositivity in donor candidates/blood donors from Northeast Brazil. Nine hundred and ninety-six donor candidates/blood donors from Foundation of Hematology and Hemotherapy of Pernambuco (HEMOPE) were interviewed regarding socioeconomic, sociodemographic, and behavioral data and analyzed for anti-HEV IgG. Anti-HEV IgG was detected using the HEV IgG (EUROIMMUN) kit. Associations between seropositivity and potential risk factors were analyzed by the χ2 test and Fisher's exact test. Seroprevalence was 0.9% (9/996), 77.77% (7/9) and 22.22% (2/9) in blood donors and donor candidates, respectively. HEV seropositivity was associated with male (OR: 11.65; CI: 0.6755-200.9; p = 0.0163), income higher than BRL 20,000/month (p = 0.0002), and lake bathing (OR: 4.553; CI: 1.391-15.25; p = 0.0258). Importantly, about 43% (3/7) of anti-HEV positive donors made their first donation more than 20 years ago, which must be taken as a warning sign, given the possibility that these individuals may have been infected after registration as donors. Finally, the report of HEV seropositivity, especially in regular blood donors, as well as the identification of potential risk factors, reinforces the need for viral screening in Brazilian blood banks.
-
LIVE
LFA TV
11 hours agoLFA TV ALL DAY STREAM - WEDNESDAY 7/23/25
11,119 watching -
LIVE
Game On!
15 hours ago $1.44 earnedJayden Daniels Can Do What Only 8 Other NFL QBs Have Done Before!
1,725 watching -
LIVE
The Bubba Army
22 hours agoTrump accuses Obama of TREASON! - Bubba the Love Sponge® Show | 7/23/25
3,076 watching -
28:26
Producer Michael
20 hours agoIS THIS MY MOST CRAZY PURCHASE YET?!
10.7K1 -
23:21
marcushouse
8 hours ago $1.10 earnedStarship Flight When!? Yea, a LOT Just Happened!
9.29K1 -
23:48
Jasmin Laine
17 hours ago“We Reject Demographic Change”—Carney’s Comment BLOWS UP as Poilievre Drops the Hammer
11.4K19 -
LIVE
BEK TV
23 hours agoTrent Loos in the Morning 7/23/2025
215 watching -
12:48
Degenerate Jay
15 hours ago $1.17 earnedUbisoft Hates Game Preservation
15.6K5 -
9:33
The Art of Improvement
21 hours ago $1.99 earnedHow to Bounce Back from Hard Times
17.9K4 -
4:53
The Official Steve Harvey
1 day ago $1.34 earnedNo Such Thing as Luck — Just God’s Grace
16.9K5