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The Amazing uses of St. Johns Wort..... But know your warnings!
Hi Ya'll, thank you for joining me again for another Medicinal Monday. I can fit a few link and Warnings in this area. Please make sure to talk to your physician before taking St. Johns Wort.
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Antidepressants
St. John's wort may interact with medications used to treat depression or other mood disorders, including tricyclic antidepressants, SSRIs, and monoamine oxidase inhibitors (MAOIs). Taking St. John's wort with these medications tends to increase side effects, and could lead to a dangerous condition called serotonin syndrome. DO NOT take St. John's wort with other antidepressants, including:
SSRIs: Citalopram (Celexa), escitalopram (Lexapro), fluvoxamine (Luvox), paroxetine (Paxil), fluoxetine (Prozac), sertraline (Zoloft)
Tricyclics: Amitriptyline (Elavil), nortriptyline (Pamelor), imipramine (Tofranil)
MAOIs: Phenelzine, (Nardil), tranylcypromine (Parnate)
Nefazodone (Serzone)
Allergy drugs (antihistamines)
St. John's wort may reduce levels of these drugs in the body, making them less effective:
Loratadine (Claritin)
Cetirizine (Zyrtec)
Fexofenadine (Allegra)
Clopidogrel (Plavix)
Theoretically, taking St. John's wort along with clopidogrel may increase the risk of bleeding.
Dextromethorphan (cough medicine)
Taking St. John's wort at the same time as dextromethorphan, a cough suppressant found in many over-the-counter cough and cold medicines, can increase the risk of side effects, including serotonin syndrome.
Digoxin
St. John's wort may lower levels of the medication and make it less effective. DO NOT take St. John's wort if you take digoxin.
Drugs that suppress the immune system
St. John's wort can reduce the effectiveness of these medications, which are taken after organ transplant, or to control autoimmune diseases. There have been many reports of cyclosporin blood levels dropping in those with a heart or kidney transplant, even leading to rejection of the transplanted organ.
Adalimumab (Humira)
Azathioprine (Imuran)
Cyclosporine
Etanercept (Enbrel)
Methotrexate
Mycophenolate mofetil (CellCept)
Tacrolimus (Prograf)
Drugs to fight HIV
St. John's wort appears to interact with at least two kinds of medications used to treat HIV and AIDS: protease inhibitors and non-nucleoside reverse transcriptase inhibitors. The Food and Drug Administration recommends that St. John's wort not be used with any type of antiretroviral medication used to treat HIV or AIDS.
Birth control pills
There have been reports of breakthrough bleeding in women on birth control pills who were also taking St. John's wort. It is possible that the herb might make birth control pills less effective, leading to unplanned pregnancies.
Aminolevulinic acid
This medication makes your skin more sensitive to sunlight. St. John's wort also increases skin sensitivity to light. Together, they may have a dangerous impact on skin sensitivity to the sun.
Reserpine
Based on animal studies, St. John's wort may interfere with reserpine's ability to treat high blood pressure.
Sedatives
St. John's wort can increase the effect of drugs that have a sedating effect, including:
Anticonvulsants, such as phenytoin (Dilantin) and valproic acid (Depakote)
Barbiturates
Benzodiazepines, such as diazepam (Valium)
Drugs to treat insomnia, such as zolpidem (Ambien), zaleplon (Sonata), eszopiclone (Lunesta), and ramelteon (Rozerem)
Tricyclic antidepressants, such as amitriptyline (Elavil)
Alcohol
Alprazolam (Xanax)
St. John's wort may speed up the breakdown of Xanax in the body, making it less effective.
Theophylline
St. John's wort can lower levels of this medication in the blood. Theophylline is used to open the airways in people with asthma, emphysema, or chronic bronchitis.
Triptans (used to treat migraines)
St. John's wort can increase the risk of side effects, including serotonin syndrome, when taken with these medications:
Naratriptan (Amerge)
Rizatriptan (Maxalt)
Sumatriptan (Imitrex)
Zolmitriptan (Zomig)
Warfarin (Coumadin)
St. John's wort reduces the effectiveness of warfarin, an anticoagulant (blood thinner).
Other drugs
Because St. John's wort is broken down by certain liver enzymes, it may interact with other drugs that are broken down by the same enzymes. Those drugs may include:
Antifungal drugs, such as ketoconazole (Nizoral), itraconazole (Sporanox), fluconazole (Diflucan)
Statins (drugs taken to lower cholesterol), including atorvastatin (Lipitor), lovastatin (Mevacor), and simvastatin (Zocor)
Imatinib (Gleevac) -- may make Gleevac less effective
Irinotecan (Camptosar) -- may speed up the rate at which Camptosar is broken down by the body, making it less effective
Some calcium channel blockers (taken to lower blood pressure)
Any medication broken down by the liver
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