2 years ago

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What is this antiaging wonder drug? Let's see how, when used off label it can help many people in many ways.
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• 500mg Metformin
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Links:
https://www.healio.com/news/endocrinology/20170207/beyond-diabetes-metformin-may-prove-to-be-a-wonder-drug
https://pubmed.ncbi.nlm.nih.gov/31405774/
https://www.ncbi.nlm.nih.gov/books/NBK518983/#:~:text=Metformin%20also%20has%20several%20non,polycystic%20ovary%20syndrome%20(PCOS).
https://www.health.harvard.edu/blog/is-metformin-a-wonder-drug-202109222605
https://clinicaltrials.gov/ct2/show/NCT02432287
https://pubmed.ncbi.nlm.nih.gov/24720592/
https://www.ahajournals.org/doi/10.1161/circ.144.suppl_1.9819
https://www.primary-care-diabetes.com/article/S1751-9918(18)30013-5/fulltext
https://honehealth.com/edge/health/benefits-of-metformin/
https://diatribe.org/can-miracle-drug-metformin-also-help-you-lose-weight
https://www.uptodate.com/contents/metformin-for-treatment-of-the-polycystic-ovary-syndrome/print
https://www.healthline.com/health/diabetes/metformin-weight-loss
https://www.researchgate.net/publication/323631830_Update_on_off_label_use_of_metformin_for_obesity
https://www.healthline.com/health/diabetes/diabetes-drug-aging

Metformin, a medication designed to control diabetes, has of late become the controversial darling of the health-conscious internet elite, who have been attracted by preliminary research suggesting it may help promote longevity, reduce dementia and prevent a whole host of other medical conditions, most recently added to the list is that of long COVID. With origins that date back to Medieval Europe, metformin has been used for decades as a powerful tool to lower blood sugar in people who already have diabetes. In those patients, it also offers cardiovascular benefits and has resulted in significant weight loss.
Now it is increasing in popularity for use in conditions that have nothing to do with diabetes. Intrigued by early studies and promotion on platforms such as TikTok and Instagram, and on health-focused blogs, vlogs and websites, people have now started seeking "off-label" prescriptions for metformin. So, off label is using a drug for a different condition, and/or at a different dosage, than it had been originally approved for by the FDA. But experts urge caution, saying there isn't enough data available yet to start recommending daily dosages of these "off-label" prescriptions.
Dr. Peter Chin-Hong of the University of California, San Francisco, when citing lack of extensive research, said "I'd be very wary about using metformin off-label at this point, the evidence has to be really strong if you take a drug for a particular indication in which there's not a lot of good data."
Stanford University endocrinologist, Dr. Marilyn Tan MD said: ‘While it's unlikely to do harm’ - “Certainly, a lot of young healthy people are looking into taking it with hopes of kind of optimizing their health and 'biohacking' to improve their longevity down the line. There's also no proven benefit from any randomized controlled trial in terms of anti-aging effects…It's not FDA-approved for any of these other indications."
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