Indianapolis Colts vs Jacksonville Jaguars Predictions and Odds | Colts vs Jags Preview | Week 6

Indianapolis Colts vs Jacksonville Jaguars betting picks, predictions and odds for their NFL Week 6 showdown at Lucas Oil Stadium. Direct from Las Vegas, our panel of professional sports handicappers look at the Vegas odds and offer their expert NFL analysis on this AFC South clash between the Jaguars and Colts. At the time of posting, the WagerTalk Live Odds screen is showing Indianapolis as a 2-point home favorite over the visitors from Jacksonville, with the over/under sitting at 42 points.

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