San Francisco 49ers vs Kansas City Chiefs Predictions and Odds | 49ers vs Chiefs Preview | Week 7

San Francisco 49ers vs Kansas City Chiefs betting picks, predictions and odds for their NFL Week 7 showdown in Santa Clara. Direct from Las Vegas, our panel of professional sports handicappers look at the Vegas odds and offer their expert NFL analysis on this cross-conference clash between the 49ers and Chiefs. At the time of posting, the WagerTalk Live Odds screen is showing Kansas City as a 2.5-point road favorite at San Francisco, with the over/under sitting at 48.5 points.

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