NFL Week 18 Picks and Predictions | Arizona Cardinals vs San Francisco 49ers Betting Preview

🏈 Since Jimmy Garoppolo went down with an injury, the San Francisco 49ers are 5-0 with rookie Brock Purdy at the helm. This week the Niners host the banged-up Arizona Cardinals at Levi's Stadium. At the time of this posting, odds have San Francisco as -14 home-favorites, and the total is sitting at 40.5. Rob Veno breaks down both sides and offers his thoughts on a first-half wager.

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