cas: 17650-98-5 ceruletide

cas: 17650-98-5 ceruletide
CBNumber: CB2384634
Chemical Name: CAERULEIN
Molecular Formula: C58H73N13O21S2
Formula Weight: 1352.4
CAS No.: 17650-98-5
Caerulein is a specific decapeptide similar in action and composition to the natural gastrointestinal peptide hormone cholecystokinin. It exerts stimulatory effects on the gastric, biliary, and pancreatic secretion, as well as on certain smooth muscles.
Ceruletide (INN), also known as cerulein or caerulein, is a ten amino acid oligopeptide that stimulates smooth muscle and increases digestive secretions. Ceruletide is similar in action and composition to cholecystokinin. It stimulates gastric, biliary, and pancreatic secretion; and certain smooth muscle. It is used in paralytic ileus and as diagnostic aid in pancreatic malfunction. It is used to induce pancreatitis in experimental animal models.
Ceruletide is a synthetic decapeptide that resembles cholecystokinin and causes contraction of the gallbladder. It has been used instead of the traditional “fatty meal” in cholecystography, as an aid in X-ray examination of the small bowel, and to evaluate exocrine pancreatic function ; it has also been used to treat postoperative ileus, intestinal atonia, and chronic fecal stasis , and to treat retained bile stones