The Next Pandemic - How bad might things get? How should we prepare?

Pandemic preparedness is a hot topic. Why might the next pandemic be much worse that the COVID-19 pandemic? To answer that question, we need to consider the epidemiological factors like disease transmission, immunological response and virus mutation. We also need to understand R0, Case Fatality Rate, the incubation and infectivity periods and other factors that feed into how bad a pandemic might get. Understanding the epidemiology will help us plan a public health and global health strategy.