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Https://www.vox.com/future-perfect/2022/10/19/23412562/covid-omircron-gain-of-function-research-engineered-pandemic-biosafety

“The Omicron S-bearing virus robustly escapes vaccine-induced humoral immunity ... yet unlike naturally occurring Omicron, efficiently replicates in cell lines and primary-like distal lung cells,” their just-released preprint paper announces. “In K18-hACE2 mice [a kind of mouse specifically engineered to be vulnerable to Covid], while Omicron causes mild, non-fatal infection, the Omicron S-carrying virus inflicts severe disease with a mortality rate of 80%.”