Safely Eat a Donut a Day, Micro-Dosing Longevity Supplements, 7 Aging Tenants | Dr. Sandra Kaufmann

If you follow "anti-aging" science, you've surely heard of David Sinclair. Known for putting NAD precursors and resveratrol on the map. But you might not know of Dr. Sandra Kaufmann. She's digging into the emerging new research and synthesizing it for us. Then put it into an elegant, easy-to-understand matrix of longevity supplements.

This is part one of the interview, and in it we discuss her system and how to build your ideal longevity pyramid. Next week, we'll cover some of her favorite emerging longevity molecules.

📕  Video chapters
0:00 Introduction
0:50 Katalyst.Fit EMS system workout
3:16 Dr. Kaufmann's background
4:16 Longevity science changes since her 2018 book
5:20 Why seven tenants of aging?
6:45 Aging tenant #1: DNA alterations over time
7:28 Aging tenant #2: energy source for cells
8:09 Aging tenant #3: primary longevity pathways
9:34 Aging tenant #4: quality control
10:52 Aging tenant #5: inflammation control
11:32 Aging tenant #6: individual cell requirements
11:46 Aging tenant #7: waste management
12:34 Dr. Kaufmann's longevity agent rating system
14:19 How to activate SIRT3
15:35 Why certain bodily systems usually fail first with age
16:31 Circadian rhythm determines sleep ability
16:59 Sirtuins drive circadian rhythms
17:15 NAD is the fuel required for sirtuins to work
18:17 Kaufmann protocol to mitigate blood glucose spikes & AGEs
21:46 Glucose sticks to three particular amino acids
22:45 Exogenous lactoferrin can shutdown inflammation
26:27 How to quantify the effects of her blood sugar protocol
27:58 Mitigating oxidized (inflammatory) PUFAs and fats
28:23 Astaxanthin and delphinidin as powerful free radical scavengers
28:41 Evaluating the long-term safety of longevity supplements
29:33 Dr. Kaufmann micro-doses 72+ longevity ingredients
31:24 Does she cycle her longevity supplements?
31:42 Crucial distinction between adjuvants and supplements
32:43 How to manage a huge stack of longevity products
35:10 Benefits of micro-dosing anti-aging compounds

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📝 About our guest
In the realm of Longevity, Dr. Sandra Kaufmann is the author and creator of the Kaufmann Protocol, a systematic explanation of why we age on a cellular basis coupled with an organized system to delay the aging process. This theory was introduced in the book, The Kaufmann Protocol: Why We Age and How to Stop it, which has been recognized by many longevity leaders as the go-to tome for understanding the aging process. More recently she wrote, The Kaufmann Protocol: Aging Solutions.

Sandy is well respected in the longevity community for presenting viable and scientifically based aging solutions that are available to everyone. She appears on weekly podcasts around the world, sits on longevity boards, and has spoken at innumerable health and biohacking seminars.

🔑 Key takeaways
- Seven tenant aging system encapsulates the current information and is succinct enough to remember
- "Lack of sleep is a failure of your circadian rhythms"
- Sirtuins power the circadian rhythm and they require NAD to function
- Dr. Kaufmann uses a 7-step process to offset the biological damage of consuming a donut every day
- Micro-dosing many longevity agents creates a powerful synergy
- How to evaluate the long-term safety and efficacy of supplements

🔗 Links
- Full episode show notes: https://mindbodypeak.com/74
- Music by Luke Hall: soundcloud.com/c_luke_hall

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- Subscribe: https://mindbodypeak.com/subscribe
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