Scientists Find Antibodies That Neutralize All COVID Strains

YouTube = https://www.youtube.com/channel/UCGobVm8zABdoMmv8Fbc1wMg

Locals = https://sweethomesa.locals.com/

POPULIST REVOLT = https://populistrevolt.com

https://www.theepochtimes.com/scientists-find-antibodies-that-neutralize-all-covid-strains_4793641.html?utm_source=goodeveningnoe-ai&src_src=goodeveningnoe-ai&utm_medium=email&utm_campaign=gv-2022-10-13-ai-28&src_cmp=gv-2022-10-13-ai-28&est=3DR8EvwEIr4zXwSeFbz9UK2hbMPjHzNcFhj8e5g09QYp1g%2F%2Bq4f4uGSdMSyuwQ9o

Two antibodies have been uncovered that are so effective at neutralizing COVID-19 — and all of its variants — that they believe the antibodies could serve as an “effective substitute for vaccines”
The antibodies — TAU-1109 and TAU-2310 — bind to a different area of the spike protein than other antibodies, one that doesn’t undergo many mutations
TAU-1109 is 92% effective at neutralizing the omicron strain and 90% effective at neutralizing the delta strain
TAU-2310 has an efficacy rate of 84% at neutralizing omicron and a 97% efficacy rate against the delta variant
The researchers believe that with effective antibody treatment, “we will not have to provide booster doses to the entire population every time there is a new variant”
Researchers at Tel Aviv University revealed two antibodies that are so effective at neutralizing SARS-CoV-2 — and all of its variants — that they believe the antibodies could serve as an “effective substitute for vaccines.”1 One of the glaring failures surrounding COVID-19 shots is their lack of effectiveness against emerging COVID-19 strains.

By choosing the spike protein on which to base COVID-19 shots, scientists picked a protein that not only was known to be toxic to humans but was not the part of the virus that prompted the best immune response.

Spike protein mutates rapidly, which essentially destroys virtually any protection that the shot provides shortly after it’s given. The end result is a seemingly never-ending series of annual shots and boosters, which can only offer rapidly waning protection. If the Israeli researchers’ findings are verified and the antibodies turn out to be as effective as suspected, it could eliminate COVID-19 booster shots entirely.2

Previous Antibody Treatments Had Mixed Results

The U.S. Food and Drug Administration (FDA) has authorized multiple monoclonal antibody (mAb) cocktails for the treatment of COVID-19. However, as variants emerged, their effectiveness varied, with some becoming ineffective and others retaining their activity.

“This indicates that some antibodies elicited by infection are more variation-sensitive than others, and that antibody breadth of specificity, and not only potency, should be considered,” the researchers, from the department of clinical microbiology and immunology at Tel Aviv University’s Sackler Faculty of Medicine,3 wrote in the journal Communications Biology.4

For instance, in January 2022, the FDA limited the use of two monoclonal antibody treatments — bamlanivimab and etesevimab, which are administered together, and REGEN-COV (casirivimab and imdevimab) — to patients infected with a variant known to be susceptible to them.5 The two antibody treatments mentioned had lost much of their effectiveness against the omicron variant, leading to the usage restriction in people infected with omicron.

On the other hand, in February 2022, the FDA issued an emergency use authorization (EUA) for a monoclonal antibody treatment known as bebtelovimab, which retained activity against the omicron variant.6 According to the FDA

The way the antibodies bind to the spike protein may hold the key to their ultimate effectiveness against various strains. In previous research conducted in October 2020, lead study author Natalia Freund and colleagues isolated nine antibodies from people who recovered from the original COVID-19 strain in Israel. Freund stated in a news release

The featured study picks up where the October 2020 study left off, revealing two antibodies — TAU-1109 and TAU-2310 — that bind to a different area of the spike protein — one that doesn’t undergo many mutations — making them capable of neutralizing all known strains of COVID-19. According to Freund

Specifically, they found TAU-1109 is 92% effective at neutralizing the omicron strain and 90% effective at neutralizing the delta strain. TAU-2310 has an efficacy rate of 84% at neutralizing omicron and a 97% efficacy rate against the delta variant.10 The study was conducted in collaboration with the University of California at San Diego, where the two antibodies were sent for additional testing against live viruses in laboratory cultures.

The antibodies were also tested against pseudoviruses at Bar-Ilan University in the Galilee. “The results were identical and equally encouraging in both tests,” according to a news release.11 What’s interesting is that the mutating virus may have played a part in making the two antibodies so effective. Freund explained