Florida State Surgeon General Dr. Joseph A. Ladapo Issues New Mrna COVID-19 Vaccine Guidance
Florida State Surgeon General Dr. Joseph A. Ladapo Issues New Mrna COVID-19 Vaccine Guidance
Tallahassee, Fla. — Today, State Surgeon General Dr. Joseph A. Ladapo has announced new guidance regarding mRNA vaccines. The Florida Department of Health (Department) conducted anexit disclaimer iconanalysis through aanalysisself-controlled case series, which is a technique originally developed to evaluate vaccine safety.
This analysis found that there is an 84% increase in the relative incidence of cardiac-related death among males 18-39 years old within 28 days following mRNA vaccination. With a high level of global immunity to COVID-19, the benefit of vaccination is likely outweighed by this abnormally high risk of cardiac-related death among men in this age group. Non-mRNA vaccines were not found to have these increased risks.
As such, the State Surgeon General recommends against males aged 18 to 39 from receiving mRNA COVID-19 vaccines. Those with preexisting cardiac conditions, such as myocarditis and pericarditis, should take particular caution when making this decision.
“Studying the safety and efficacy of any medications, including vaccines, is an important component of public health,” said Surgeon General Dr. Joseph Ladapo. “Far less attention has been paid to safety and the concerns of many individuals have been dismissed – these are important findings that should be communicated to Floridians.”
References
1. Petersen I, Douglas \, Whitaker H. Self controlled case series methods: an alternative to standard
epidemiological study designs. BMJ. 2016;354:;i4515. doi:10.1136/bmj.i4515
2.
Nafilyan V, Bermingham C, Ward IL, et al. Risk of death following SARS-CoV-2 infection or COVID-19
vaccination in young people in England: a self-controlled case series study. medRxiv. Published online
January 1, 2022:2022.03.22.22272775. doi:10.1101/2022.03.22.22272775
3.
Whitaker H, Farrington P, Spiessens B, Musonda P. Tutorial in Biostatistics: The self-controlled case
series method. Stat Med. Published online 2006:1768-1797. doi:https://doi.org/10.1002/sim.2302
4.
Hubbard R, Lewis S, West J, et al. Bupropion and the risk of sudden death: a self-controlled case-
series analysis using The Health Improvement Network. Thorax. 2005;60(10):848.
doi:10.1136/thx.2005.041798
5. Whitaker H. Using R for Self-Controlled Case Series Studies.; 2022. https://sccs-studies.info/r.html
6. Weldeselassie, YG, Whitaker, HJ, Farrington, CP. Use of the self-controlled case-series method in
vaccine safety studies: review and recommendations for best practice. Epidemiol Infect.
2011;139(12):1805-1817. doi:10.1017/S0950268811001531
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