Why Elderberry should make you angry!

Why Elderberry should make you angry: the criminal underuse of herbal medicines in COVID-19

BOOK: http://thesecretlifeofchocolate.com/
Practice website: http://nocturnalherbalist.com/v2/
Association of Master Herbalists practitioner profile: https://associationofmasterherbalists.co.uk/user/marcospatchett/
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TIMESTAMPS
00:01:21 Intro
00:04:31 Medical Ethics - the precautionary principle
00:06:17 Risk-benefit ratio
00:07:50 Distorting effect of profit
00:10:32 Elderberry and COVID-19
00:12:40 Clinical trials update
00:13:24 Problems with funding
00:17:51 Elderberry as an adjunct in COVID-19
00:22:58 Elderberry in URT infections
00:24:50 Elderberry in vitro SARS CoV-2 spike protein inhibition
00:27:15 Elderberry vs. viral "haemagglutinin spikes"
00:29:33 The Flexner report
00:35:55 Issues with Flexner's rubric
00:42:15 Contemporary relevance of the Flexner report
00:44:03 Other plants in COVID-19
00:44:28 Liquorice (Glycycrrhiza glabra) revisited
00:56:23 Mulberry (Morus alba) revisited
00:59:58 Black Seed (Nigella sativa)
01:11:06 N. sativa clinical trial in COVID-19
01:18:04 Safety profile of herbal medicines in COVID-19
01:24:00 Concluding remarks

REFERENCES
Risk-benefit assessment of herbal adjuvants in COVID-19 (2020) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542597/

Book: Edwards, S., de Costa Rocha, I., Williamson, E., & Heinrich, M. (2015). Phytopharmacy: an Evidence-Based Guide to Herbal Medicinal Products. Wiley Blackwell: Sussex, U.K.

The effects of Sambucus nigra berry on acute respiratory viral infections: A rapid review of clinical studies (2020): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443157/

2021 in vitro study: Elderberry inhibits COVID-19 ACE-2 receptor binding. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969829/

Iranian clinical trial of Elderberry in COVID-19 https://www.irct.ir/trial/46958

East Kent Hospital clinical trial of Elderberry in COVID-19 https://www.ekhuft.nhs.uk/patients-and-visitors/news-centre/latest-news/east-kent-researchers-trial-black-elderberry-liquid-as-a-treatment-for-covid-19/ • Subsequent reportage: https://localrags.co.uk/2021/06/26/people-in-kent-wanted-to-help-research-treatments-into-covid-19/

The Flexner report (1910): https://archive.org/details/carnegieflexnerreport/page/n22/mode/1up?view=theater

Yale journal retrospective on the Flexner report: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178858/#:~:text=The%20Flexner%20Report%20of%201910%20transformed%20the%20nature,model%20as%20the%20gold%20standard%20of%20medical%20training.

The Flexner report and its effects on CAM and Psychiatry in North America, free journal article: https://www.researchgate.net/publication/235368754_The_Flexner_Report_of_1910_and_Its_Impact_on_Complementary_and_Alternative_Medicine_and_Psychiatry_in_North_America_in_the_20th_Century Blog on the “Rockefeller/Carnegie takeover of Western medicine” http://ian-faulkner.com/rockefeller-bigpharma/#:~:text=%E2%80%9CWhen%20Flexner%20researched%20his%20report%2C%20%E2%80%9Cmodern%E2%80%9D%20medicine%20faced,cure%20illness%20as%20tantamount%20to%20quackery%20and%20charlatanism.

Action of Glycyrrhizin in COVID-19 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270278/

Glycyrrhiza compounds activity https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309308/

Glycyrrhiza – whole herb in COVID-19 review https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020229/

Mulberry – M. alba roots contain resveratrol with anti-COVID-19 activity https://pubmed.ncbi.nlm.nih.gov/33170382/;
Root bark used in TCM to drain fluid from lungs https://www.sciencedirect.com/topics/immunology-and-microbiology/morus-alba
- see article by Tai Lahans in Integrating Conventional and Chinese Medicine in Cancer Care, 2007 Protease inhibitors from M.alba show promise as antiviral agents vs. COVID-19 – molecular models show they may prevent viral entry into cells (Free full-text) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009078/

Nigella sativa – free full-text paper https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675410/
Nigella sativa supplementation plus regular exercise proposed as prophylactic against COVID-19, free full-text paper https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162633/
Nigella sativa open-label randomized clinical trial in acute COVID-19 infection https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364675/

Risk-benefit assessment of herbal anti-COVID agents: evidence and arguments in favour of immediate implementation of M. alba, Lonicera japonica, and others; Glycyrrhiza to be used with more caution. [Full text] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840405/
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