3 months ago

Ivermectin, Russel Brand warning rationalle

Ivermectin

https://www.covid19treatmentguidelines.nih.gov/therapies/antiviral-therapy/

https://www.covid19treatmentguidelines.nih.gov/therapies/antiviral-therapy/ivermectin/

Direct from official FDA site

Ivermectin is a Food and Drug Administration (FDA)-approved antiparasitic drug,

used to treat several neglected tropical diseases,

including onchocerciasis, helminthiases, and scabies.

For these indications, ivermectin has been widely used and is generally well-tolerated

Ivermectin is not approved by the FDA for the treatment of any viral infection.

Proposed Mechanism of Action and Rationale for Use in Patients With COVID-19

(in vitro studies)

suggest that ivermectin acts by,

Inhibiting host importin nuclear transport proteins

Interfere with SARS-CoV-2 spike protein attachment to the human cell membrane

Some studies of ivermectin have also reported potential anti-inflammatory properties

Shown to inhibit replication of SARS-CoV-2 in cell cultures

COVID-19 medical misinformation policy

https://support.google.com/youtube/answer/9891785
https://support.google.com/youtube/answer/11161123

If you're posting content

Don't post content on YouTube if it includes any of the following:

Treatment misinformation:

Content that claims that there's a guaranteed cure for COVID-19

Content that recommends use of Ivermectin or Hydroxychloroquine for the treatment of COVID-19

Categorical claims that Ivermectin is an effective treatment for COVID-19

Claims that Ivermectin and Hydroxychloroquine are safe to use in the prevention of COVID-19

Other content that discourages people from consulting a medical professional or seeking medical advice

Prevention

misinformation: Content that promotes prevention methods that contradict local health authorities or the WHO.

Claims that there is a guaranteed prevention method for COVID-19

Claims that any medication or vaccination is a guaranteed prevention method for COVID-19

Content that recommends use of Ivermectin or Hydroxychloroquine for the prevention of COVID-19

Claims that Ivermectin and Hydroxychloroquine are safe to use in the prevention of COVID-19

Monitoring, Adverse Effects, and Drug-Drug Interactions

The FDA first issued a warning in April 2020 that ivermectin intended for use in animals should not be used to treat COVID-19 in humans. This warning was updated and reiterated in 2021.

https://www.fda.gov/consumers/consumer-updates/why-you-should-not-use-ivermectin-treat-or-prevent-covid-19

FDA, Recommendation

The Panel recommends against the use of ivermectin for the treatment of COVID-19, except in clinical trials

The Panel will continue to review emerging data on ivermectin use, including the results from 2 large, ongoing randomized controlled trials.

Clinical Trials

Several clinical trials evaluating the use of ivermectin for the treatment of COVID-19 are currently underway or in development.

Please see ClinicalTrials.gov for the latest information.

Search of: Ivermectin | COVID-19 - List Results - ClinicalTrials.gov

Bangkok

Egypt

Malaysia

Is this one of the two?

https://www.principletrial.org/news/ivermectin-to-be-investigated-as-a-possible-treatment-for-covid-19-in-oxford2019s-principle-trial

Ivermectin to be investigated in adults aged 18+ as a possible treatment for COVID-19 in the PRINCIPLE trial
23 June 2021

Time line

https://www.principletrial.org/news/the-principle-trial-two-years-on

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