Curcumin

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Curcumin is a polyphenol extracted form Curcuma longa, is a compound commonly used as a food additive and dietary spice in Asia, especially in India. It is the major component that give turmeric, its yellow distinct color. It has been used in herbal medicine, as a treatment for osteoarthritis, depression, itching, colds and Flu. Recently, studies have evidenced that aging model organisms, treated with curcumin and its metabolites has been shown to have longer mean lifespan. This could attributed for its anti-cancer, anti-aging, anti-microbial, and anti-inflammatory properties. Moreover, it is also one of the best antioxidants that reduce age-related cellular damage induced by reactive oxygen species. Curcumin is also proposed as a compound that can induce hormesis. Hormesis, is a chemical and environmental factor, that can be beneficial to organism at low doses, activating biological events, in the organism that affect lifespan and stress response. Through hormesis, curcumin can stimulate heat shock proteins, that can stabilize damaged proteins, which are toxic to cells and can accumulate during aging. An example of heat shock protein is H-S-P-70. Curcumin has been suggested increase H-S-P-70 expression in Indian population compared to the US, which is associated to the over 4-fold lower incidence of Alzheimer’s disease in India. Moreover, it can also be an effective anticancer agent, by inducing apoptosis and interfering with cell proliferation, and decreasing the production of pro-inflammatory molecules that cause initiation and development of cancer. Recently, it has been suggested, to be a potential therapeutic agent, for major eye diseases. For example, in diabetic retinopathy, curcumin normalizes diabetic microvasculature, and attenuate shrinkage and micro-aneurysms as it provides protective role, against oxidative stress and decrease vascular endothelial growth factor. It's important to talk to your doctor or other professional before beginning any sort of supplementation or treatments. Feel free to contact us if you want us to give you the contact information of professionals who work with our network.
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Topic related to: LONGEVITY, HEALTH, IMMUNITY, INFLAMMATION, ANTIAGING, LIFESPAN, Mitochondria, HEALING, SUPPLEMENTS, HEALTHY LIFE, IMMUNE SYSTEM, Curcumin, curcuma, turmeric.

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