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RAPAMYCIN | Anti- AGING compound | mTOR INHIBITOR
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Rapamycin is an FDA approved drug that has long been used as an immunosuppressant. Recently, interest has been growing regarding its ability to extend lifespan and prevent age-related conditions in various organisms, from fruit flies to humans. Most studies have used mouse models of accelerated cancer, and studies show an increase in lifespan as well as reduction in the progression of the neoplastic tumors. According to studies rapamycin contributes to lifespan mainly by blocking the TOR enzymes. TOR stands for target of rapamycin. These enzymes are activated in the presence of sufficient nutrient to fuel protein synthesis, which promotes cell growth and cell cycle progression, at the same time inhibiting autophagy. Hyperactive T-O-R has been shown to increase cell senescence and cell death, especially in neuronal degeneration disorders. While inhibition of T-O-R signaling can protect cells against any mechanism that promote cell death, especially in neurodegenerative disorders. Recently, another mechanism has been discovered through which rapamycin extends lifespan. An international team of researchers have found that rapamycin increases histone proteins,around which the double-helix DNA are wrapped to allow the DNA to fit in the nucleus. The researchers have found that the increased levels of certain histone proteins in a specific gut cell type reduced tumour growth, improved gut health, and extended lifespan of the animals. As a longevity-promoting compound, it is most effective if administration starts at healthy stage, because it is more effective in preventing diseases associated with aging, rather than treating them. It's important to talk to your doctor or other professional before beginning any sort of supplementation or treatments. Feel free to contact us if you want us to give you the contact information of professionals who work with our network.
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Topic related to: LONGEVITY, HEALTH, IMMUNITY, INFLAMMATION, ANTIAGING, LIFESPAN, Mitochondria, HEALING, SUPPLEMENTS, HEALTHY LIFE, IMMUNE SYSTEM, LONGEVITY PROTOCOL, Rapamycin.
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