Science of Spermidine for Longevity, Autophagy & More | Leslie Kenny @ Oxford Healthspan

Spermidine is one of the best and most popular longevity supplements that improves 6 of the 9 hallmarks of aging.

Leslie Kenny from Oxford Healthspan joins us to talk about ancient Japanese Longevity secrets, the health benefits of spermidine, and what to look for in quality products.

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📕  Video chapters
0:00 Introduction
0:26 Benefits of HRT
2:18 What is Healthspan
3:18 The Oxford Longevity Project
3:42 Should aging be classified as a disease
4:21 What is spermidine
6:24 The 9 tenants of aging
10:06 The role of spermidine in health
11:28 Whole food sources of spermidine
11:57 Health benefits of Natto (autophagy activator)
13:51 What is autophagy
17:31 Consequences of spermidine deficiency
22:09 Spermidine and immunity
23:52 Spermidine and cognition
24:36 Spermidine and cardiovascular health
25:42 Link between centenarians and spermidine levels
26:30 Plant-based and carnivore-friendly sources of spermidine
27:57 Secrets of the Japanese Longevity Scrolls
29:37 Taoism, Tantra & More
31:48 Benefits of semen retention
37:56 How to identify the best spermidine supplements
39:25 Prebiotic fibers can stimulate the body to produce spermidine
41:36 LMK512 spermidine-producing bacterial strain
43:25 Safe spermidine dose (as determined by European Food Safety)
43:57 Why wheat germ-based spermidine is the best
44:06 The 3 vital polyamines in ideal spermidine supplements
44:44 Spermidine with spermine rebalances numerous hormones

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📝 About our guest
Oxford Healthspan was founded by Leslie Kenny, a Southern Californian entrepreneur and graduate of both Berkeley and Harvard, whose life was turned upside down when she was diagnosed with lupus and rheumatoid arthritis in her 30s. When her doctors told her lupus had a life expectancy of five years and that RA could only be managed, not cured, she set out to optimize her health as best she could with safe, natural solutions.

She went back to school at the Institute for Integrative Nutrition in NYC, became a Bulletproof coach under health pioneer Dave Asprey, and took on health coaching clients worldwide. At the same time, she began helping life science academics at European universities, including Oxford, to raise money for their discoveries. She met a scientist who introduced her to a promising compound called spermidine. The science was compelling – one scientist even called it “an anti-aging vitamin” in a published scientific journal – and it was safe. Still, because it was natural, food-derived, and not a profitable drug, no one was interested in promoting it. Spermidine wasn't available in the US, so she decided to bring it to the US herself.

Today, at age 56, Leslie is living proof that we can get better with age, so long as we take responsibility for our health and meet our doctors halfway.

🔑 Key takeaways
- When we lose the body's innate ability to regenerate itself, we've lost half the battle
- Spermidine is so vital to protecting human health that scientists may reclassify it as an essential nutrient
- Spermidine protects hormone levels, cardiovascular and immune systems, brain health, and more
- Spermidine is one of the most potent autophagy triggers

🔗 Links
- Full episode show notes: https://mindbodypeak.com/46
- Music by Luke Hall: soundcloud.com/c_luke_hall

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Disclaimers:
Nothing posted on this channel is medical advice or a substitute for advice from your physician or healthcare provider. Always contact your healthcare professional with any questions about a medical condition or your personal health. Additionally, some of the links provided above are affiliate links. They don't cost you anything, but I make a tiny commission from the sale. Honesty is key on my channel, and thank you for your support! You may read the full disclaimer here: https://outliyr.com/disclaimers