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PQQ is an anti oxidant that comes from soil, soil bacteria and food sources such as parsley and tomato. It is known for its ability to protect the mitochondrial activity from damages caused by oxidative stress. It also affects several biological processes, influencing mitochondriogenesis, reproduction, growth, and aging. PQQ serves as an enzyme cofactor, especially to glucose or alcohol dehydrogenases. It also plays an essential role in dehydrogenases such as lactate dehydrogenase. PQQ binds to LDH and enhances NADH oxidation to NAD+ and pyruvate production. Aging is associated with the depletion of N AD + levels. NAD plus is a substrate for the deacylation reactions catalyzed by sirtuins, which are proteins involved in cell signaling. Restoring NAD+ levels through PQQ supplementation has been reported to slow or reverse aging and also delay the progression of aging-related diseases. Aside from its effect on NAD+ levels, PQQ supplementation has been reported to improve cognitive function and memory by reducing pro-inflammatory proteins such as C-reactive protein, interleukin 6 levels, and plasma malonaldehyde. As an antioxidant, it prevents and neutralizes the oxidative damage of the nervous system, and hence maintains its cognitive function.
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Topic related to: LONGEVITY, HEALTH, IMMUNITY, INFLAMMATION, ANTIAGING, LIFESPAN, Mitochondria, HEALING, SUPPLEMENTS, HEALTHY LIFE, IMMUNE SYSTEM, LONGEVITY PROTOCOL.
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