Rutin

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Rutin, also called as rutoside, quercetin-3-rutinoside, and sophorin is a bioflavonoid that is found in many plants, including passionflower, figs, rose hips, and asparagus. Rutin has been demonstrated to exhibit a number of pharmacological activities, including antioxidant, cytoprotective, vasoprotective, anticarcinogenic, neuroprotective, and cardioprotective activities. It has been shown to have therapeutic properties against neurodegenerative diseases due to its anti inflammatory and antioxidant activities. The manipulation of radical oxidative species and pro inflammatory molecules may be an effective therapy option to delay the development and progression of neurodegenerative diseases. Due to its anti inflammatory and antioxidant properties, rutin has been demonstrated to have therapeutic effect on chronic rheumatoid arthritis. Rutin has been shown to have antidiabetic effects. Chronic administration of rutin in diabetic rats has been reported to decrease plasma glucose, augmentation in insulin levels, and restitution of glycogen content and glycolytic enzymes. Moreover, this bioflavonoid has been known to have anti hypercholesterolemic effects. In a study conducted on experimental animal models of hypercholesterolemia, rutin has significantly reduced plasma triglyceride levels and levels of total cholesterol. Lastly, rutin has been reported to have protective effects against osteoporosis. Rutin inhibits osteoclast formation by decreasing oxygen reactive species and TNF-alpha by inhibiting activation of NF-kappa-B.
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Topic related to: LONGEVITY, HEALTH, IMMUNITY, INFLAMMATION, ANTIAGING, LIFESPAN, MITOCHONDRIA, HEALING, SUPPLEMENTS, HEALTHY LIFE, IMMUNE SYSTEM, LONGEVITY PROTOCOL.

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