Sirtuins

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Sirtuins
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Sirtuins are a class of proteins that seem to regulate some aspect of the lifespan of cells. They have been found to be activated by certain compounds, and have been shown to increase lifespan in animals. The most well-known example is resveratrol which has been shown to activate Sirtuin 1 (SIRT1) and extend the life of yeast, worms, flies, and mice.

SIRT1 is a protein located in the nucleus of cells that regulates gene transcription, making it a potential target for anti-aging drugs. SIRT1 may also play a role in aging and cancer, as well as synaptic plasticity, memory formation, learning and other functions.

The Sirtuins are known to regulate metabolism, cellular aging, and circadian rhythm.

Sirtuins may serve as a biomarker for life-threatening conditions, including heart disease and Type II diabetes. Sirtuins play also an important role in protecting cells from oxidative stress.

Collectively, they have been used as a biomarker of aging or longevity.

Some research has shown that Sirtuins can be activated by resveratrol, which is a compound found in grape skins and wine.

Sirtuins are activated also by calorie restriction, which is the practice of reducing calorie intake without malnutrition.

Sirtuin deficiency is a condition where the body does not produce enough sirtuin proteins. This can happen because of an inherited gene mutation or because of an acquired condition, such as kidney disease or malnutrition.

The most common symptoms of sirtuin deficiency are: fatigue, weight gain, and a loss in muscle mass.

There are two ways to know if you have a sirtuin deficiency: genetic testing or blood tests for the level of sirtuin protein in your blood.

We would like to hear about your own experience with this topic. Leave a comment. Lastly, remember that it is important to talk to your doctor or other professional before beginning any sort of supplementation or treatment. Feel free to contact us if you want us to give you the contact information of professionals who work with our network.
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Topic related to: LONGEVITY, HEALTH, IMMUNITY, INFLAMMATION, ANTIAGING, LIFESPAN, Mitochondria, HEALING, SUPPLEMENTS, HEALTHY LIFE, IMMUNE SYSTEM, LONGEVITY PROTOCOL, sirtuin.

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