Depression has physical manifestations inside the brain

And it's not just behavioral symptoms.Depression has physical manifestations inside the brain.First of all,there are changes that could be seen with the naked eye and X-ray vision.These include smaller frontal lobes and hippocampal volumes.On a more microscale,depression is associated
with a few things:the abnormal transmission or depletion
of certain neurotransmitters,especially serotonin, norepinephrine,
and dopamine,blunted circadian rhythms,or specific changes in the REM and slow-wave parts of your sleep cycle,and hormone abnormalities,such as high cortisol and deregulation of thyroid hormones.