Spinal Tap Results

Today we will be covering the results of my Spinal Tap. Below I’ve included the articles referenced in the video as well as my CSF findings. Abnormal findings indicated by ( ! ) prefix.

Brain Barriers and brain fluids research in 2020...: https://fluidsbarrierscns.biomedcentral.com/articles/10.1186/s12987-021-00258-z

Next-Generation Sequencing of Cerebrospinal Fluid...: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018529/

Clinical associations of anti-Smith antibodies in PROFILE: a multi-ethnic lupus cohort: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475431/

IgG levels in cerebrospinal fluid of patients with central nervous system manifestations of systemic lupus erythematosus: https://www.sciencedirect.com/science/article/abs/pii/0090122972900025

( ! ) CELL COUNT DIFF, CSF
CELL COUNT, CSF[334432030] Final result
( ! ) DIFFERENTIAL, CSF[336854000] Abnormal Final result

CULT, CSF BACTI
Culture Report:
No growth

GRAM SMEAR ONLY, STAT
GRAM STAIN RESULT No organisms seen No organisms seen
SMEAR PREPARATION Cytospin
SOURCE BODY SITE CSF

GLUCOSE, CSF
Component Your Value Standard Range
GLUCOSE CSF 54 mg/dL 40 - 70 mg/dL

HSV QUALITATIVE PCR, CSF
Component Your Value Standard Range
HSV-1 QUALITATIVE PCR, CSF Undetected -
HSV-2 QUALITATIVE PCR, CSF Undetected -

CRYPTOCOCCAL ANTIGEN- CSF
Component Your Value Standard Range
CRYPTO AG, CSF Negative Negative

PROTEIN, CSF
Component Your Value Standard Range
TOTAL PROTEIN CSF 29 mg/dL 15 - 45 mg/dL

VDRL CSF
Component Your Value Standard Range
VDRL Non Reactive Non Reactive

LYME ABS TOTAL ELISA, CSF
Component Your Value Standard Range
LYME AB ELISA, CSF 0.03 LIV less than 0.99 LIV

ENCEPHALOPATHY AUTOIMMUNE/PARANEOPLASTIC EVAL, CSF
ENCEPHALOPATHY INTERPRETATION, CSF SEE COMMENTS
No informative autoantibodies were detected in this
evaluation. However, a negative result does not exclude
autoimmune encephalopathy, idiopathic or paraneoplastic.
Sensitivity and specificity of antibody testing are
enhanced by testing both serum and CSF.
AMPA-R AB CBA, CSF Negative Negative
AMPHIPHYSIN AB, CSF Negative titer 1:2 titer
AGNA-1, CSF Negative titer \/1:2 titer
ANNA-1, CSF Negative titer \/1:2 titer
ANNA-2, CSF Negative titer \/1:2 titer
ANNA-3, CSF Negative titer \/1:2 titer
CASPR2-IGG CBA, CSF Negative Negative
CRMP-5-IGG, CSF Negative titer \/1:2 titer
DPPX AB IFA, CSF Negative Negative
GABA-B-R AB CBA. CSF Negative Negative
GAD65 AB ASSAY, CSF 0.00 nmol/L \/ or equal to 0.02 nmol/L
GFAP IFA, CSF Negative Negative
IGLON5 IFA, CSF Negative Negative
LGI1-IGG CBA, CSF Negative Negative
MGLUR1 AB IFA, CSF Negative Negative
NIF IFA, CSF Negative Negative
NMDA-R AB CBA, CSF Negative Negative
PCA-1, CSF Negative titer \/1:2 titer
PCA-2, CSF Negative titer \/1:2 titer
PCA-TR,CSF Negative titer \/1:2 titer

CELL COUNT, CSF
Component Your Value Standard Range
CSF APPEARANCE Clear Clear
CSF COLOR Colorless Colorless
CSF TUBE NUMBER #4
CSF WBC 1 /cu mm 0 - 5 /cu mm
CSF RBC \/1 /cu mm \/1 /cu mm

TOXOPLASMA IGG AB, CSF
Component Your Value Standard Range
TOXOPLASMA IGG, CSF \/0.90 REFERENCE RANGE: \/0.90

ENTEROVIRUS BY PCR, CSF ONLY
Component Your Value Standard Range
ENTEROVIRUS PCR FOR CSF ONLY Negative Negative

CMV PCR Qual
Component Your Value Standard Range Flag
CMV PCR QUALITATIVE Not Detected

( ! ) DIFFERENTIAL, CSF
Component Your Value Standard Range Flag
NEUTROPHIL (CSF) 0 % 0 - 6 %
( ! ) LYMPHOCYTES(CSF) 88 % 40 - 80 % H
( ! ) MONOCYTES(CSF) 12 % 15 - 45 % L
MACROPHAGES(CSF) 0 % %
EOSINOPHILS(CSF) 0 % %
BASOPHILS(CSF) 0 % %
LINING CELLS 0 % %
REACTIVE LYMPHS(CSF) 0 % %
ATYPICAL CELLS(CSF) 0 % 0.0 %
TOTAL CELL COUNTED,CSF 43

( ! ) OLIGOCLONAL BNDS/IGG SYN RATE
Component Your Value Standard Range Flag
OLIGOCLONAL BANDS SF Negative Negative
ALBUMIN, SERUM-OLI 4500 mg/dL 3500 - 5200 mg/dL
ALBUMIN, CSF 16 mg/dL 0 - 35 mg/dL
ALBUMIN INDEX-OLI 3.6 ratio 0.0 - 9.0 ratio
IGG INDEX 0.62 ratio 0.28 - 0.66 ratio
CSF/IGG ALBUMIN RATIO 0.10 ratio 0.09 - 0.25 ratio
IGG SYN RATE \/0.0 mg/d \/ or equal to 8.0 mg/d
CSF OLIGOCLONAL BANDS NUMBER 0 Bands 0 - 1 Bands
OLIGOCLONAL COMMENTS See Note
Isoelectric focusing/immunofixation revealed no oligoclonal bands
in either the CSF or the serum. This is considered to be a
negative result for oligoclonal bands. Approximately 5 percent of
patients with clinically definitive multiple sclerosis will have a
negative result.

( ! ) IGG SERUM 731 mg/dL 768 - 1632 mg/dL L
REFERENCE INTERVAL: Immunoglobulin G

IGG CSF 1.6 mg/dL 0.0 - 6.0 mg/dL

ENCEPHALOPATHY AUTOIMMUNE/PARANEOPLASTIC EVAL, SERIUM
Same results as CSF

CNS DEMYELINATING DISEASE EVAL, SERUM
Component Your Value Standard Range Flag
CNS DEMYELINATING DISEASE INTERP, SERUM SEE COMMENTS
No informative autoantibodies were detected in this
evaluation. A negative result does not preclude a diagnosis
of an inflammatory CNS demyelinating disorder.
MOG FACS, SERUM Negative Negative
NMO/AQP4-IGG Negative Negative