Probably killed by makeup. Queen Elizabeth I

Pale white skin was the signature look for the upper class in the Elizabethan era. Queen Elizabeth I's makeup represented the 16th-century ideal for women, with her porcelain skin representing nobility and earthly perfection. But to achieve that perfection, Elizabeth coated her face in lead, which slowly poisoned her body. That wasn't the only dangerous cosmetic Elizabeth used - she also rubbed mercury on her lips and likely used a mercury-based makeup remover that ate away her skin.