How To Prevent Schizophrenia Developing in At-Risk Populations

I share a series of tips that can reduce your chances (or the chances of a loved one) from going on to develop schizophrenia.Show more

((I adjusted the video framing and reshot the video (I'm still getting used to the art of video making:) I had cut-off the top of my head in the previous upload (thinking the angle was better) but it was distracting. Hang in their peeps still getting a handle on it))

The full tip list can be found here:
https://schizoprevent.blogspot.com/
It has a link to almost all the science mentioned in this video (some info is from google)

Video points:

Schizophrenia can develop at any age. 70% under 30, under 12 Extremely unlikely.
If u have close relatives it is more likely
40 to 65% twin
10% one parent
10% risk if your sibling has it
50% two parents

Animals
A dog 25% less risk between age 1 to 3
Cat doubles risk of exposed between age of 9 to 12 12 was cut off in the study

Stress
Low abuse child abuse 2.8x
low stress
Recent stressful life events 10% increase to schizophrenia
Poverty 2x Children who are liked more less likely to develop schizo
Support network unknown
Parents married less then 2 years 50% increased
2 to 4 years 30% increased risk
Likeable children at 50% lower risk mostly* not if high poverty and worsening neighborhood
Get married unknown
Ethnic difference 3.5x black 3x Hispanic in america
Bacterial infection during pregnancy 1.8 odds ratio, 2.9 in multisystematic infection, 1.6 localized infection, men 2.6 odds ratio difference, women no difference
https://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.2019.18101206

Pollution
Country vs city 2x
Pollution nitrogen dioxide cause schizo (is higher in cities)

Supplements
Vit d summer babies 20% lower than winter babies
Choline supplementation reduces risk unknown
Extreme Excess methionine in pregnancy causes schiz 2x? in extreme cases.
Fish oil 4x improvement

Drugs
No LCD ,
psychedelics, PCP, unknown , each trip increases risk
amphetamines (Ritalin causes stimulate psychoses in 0.1% of people, Meth causes it in 36.5%)
high THC skunk marijuana used daily 5x risk, smoking at least 5 times regular marijuana doubles risk

update: risk for developing schizo after drug induced phychosis (after actually losing touch with reality)

cannabis (6 studies, 34%, CI 25%–46%), hallucinogens (3 studies, 26%, CI 14%–43%) and amphetamines (5 studies, 22%, CI 14%–34%). Lower rates were reported for opioid (12%), alcohol (10%) and sedative (9%) induced psychoses

Transition of substance-induced, brief, and atypical psychoses to schizophrenia: a systematic review and meta-analysis

Benjamin Murrie, Julia Lappin, Matthew Large, Grant Sara

Schizophrenia bulletin 46 (3), 505-516, 2020

Blind people don't get schizophrenia 100%

In mice
Late stage adolescent antipsychotics prevented full blown schizo
Low intensity Exercise ameliorates many symptoms but not all

Cognitive deficits in children of schizophrenics
Children with FHR-SZ were significantly impaired compared with controls on processing speed and working memory (Cohen d= 0.50; P equals less than 0.001), executive and visuospatial functions (Cohen d= 0.28; P= .03), and declarative memory and attention (Cohen d= 0.29; P= .02) (Cohen's d is not a percent but a measure of how much group averages differ from the standard. It is impossible to change this to a percent unless you know the statistical variability of the data points)
https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2685325
But trade offs