The Myth of "Safe and Effective"

2 years ago
406

"Safe & Effective" - now where have we heard that before?
Let's dive into another pharmaceutical experiment and see how it affected future generations.

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References:
1. Institutional Corruption of Pharmaceuticals and the Myth of Safe and Effective Drugs, 2013: https://www.ftc.gov/system/files/documents/public_comments/2015/09/00062-97081.pdf
2. Leon Goldberg: Creator of DES (Diethylstilbestrol): https://www.asmalldoseoftoxicology.org/blog/2018/2/7/leon-goldberg-creator-of-des-diethylstilbestrol
3. Diethylstilbestrol (DES) in the US: https://embryo.asu.edu/pages/diethylstilbestrol-des-us
4. Gynaecomastia in Stilboestrol workers, 1944: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1035620/pdf/brjindmed00272-0029.pdf
5. Robert Meyers - D.E.S., the bitter pill, 1983: https://archive.org/details/desbitterpill00meye
6. Diana Dutton - Worse than the disease : pitfalls of medical progress, 1988: https://archive.org/details/worsethandisease0000dutt (Excellent overview of the DES story in the US)
7. Diethylstilbestrol (DES): https://en.wikipedia.org/wiki/Diethylstilbestrol#History
8. Elmer Louis Severinghaus Papers: https://search.amphilsoc.org/collections/view?docId=ead/Mss.B.Se81-ead.xml
9. Journal of a DES Daughter: https://diethylstilbestrol.co.uk/the-des-story-long-term-consequences-of-prenatal-exposure/
10. Adenocarcinoma of the Vagina — Association of Maternal Stilbestrol Therapy with Tumor Appearance in Young Women, 1971: https://www.nejm.org/doi/full/10.1056/NEJM197104222841604
11. Maternal Diethylstilbestrol a Time Bomb for Child?, 1971: https://jamanetwork.com/journals/jama/article-abstract/340089
12. Adverse Health Outcomes in Women Exposed In Utero to Diethylstilbestrol, 2011: https://www.nejm.org/doi/full/10.1056/NEJMoa1013961
13. DES in China: https://www.made-in-china.com/products-search/hot-china-products/Diethylstilbestrol.html
14. Viral social media post claims Chinese wives are secretly feeding their husbands impotency drugs to stop cheating, 2021: https://www.scmp.com/news/people-culture/article/3131400/viral-social-media-post-claims-chinese-wives-are-secretly

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