The Mad Doctor (1933) Mickey Mouse (voiced by Walt Disney)

Nightmare Material.....The Mad Doctor is a black and white Mickey Mouse animated short. It was released in 1933, in which brought the archetype of mad doctor inspired by the character of Dr. Henry Jekyll from The Strange Case of Dr. Jekyll and Mr Hyde.

Mickey Mouse (voiced by Walt Disney)
Pluto (voiced by Pinto Colvig)
The Mad Doctor (voiced by Billy Bletcher)