Episode 5/13: Carbohydrates // A Course on Abiogenesis by Dr. James Tour

2 years ago
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In this episode on carbohydrates, Dr. James Tour teaches the 1st class of compounds needed for life -- carbohydrates-- and comes right out of the gate, refuting the claimed triviality of their biomolecular synthesis. Rather than agree with the claim on the ease of polysaccharide synthesis, Dr. Tour explains the difficulty of their creation, including homochirality and the prebiotic problems facing multiple isomers, blind pathways, and polymerization and positioning. Also, Dr. Tour points out the fallacy of borrowing products from biology in prebiotic syntheses, and the challenge of early Earth blindly working through unfathomable procedures.

Video Index:
00:00 - Introduction
00:48 - Reasons & Intent of this Abiogenesis Series
02:45 - Correcting the Record on Polysaccharide & Biomolecular Synthesis
07:28 - Before Nucleotides, Ribose
09:48 - Cannizzaro vs Formose
13:01 - Eschenmoser's attempt
19:47 - Time & Equilibrium
22:18 - "homo-DNA" instead
23:36 - Real world difficulties
25:53 - Polymerization - Hooking the Sugars
42:36 - Summary and What's Next

Links in this Series | Addressing Abiogenesis & Common Misconceptions
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Series Trailer: https://youtu.be/N-RvMStTkx4
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0 - Reasons for this Series: https://youtu.be/71dqAFUb-v0
1 - Introduction to Abiogenesis: https://youtu.be/NqoVxwdWWpg
2 - Primordial Soup: https://youtu.be/tNbl-g8QoAg
3 - Hype: https://youtu.be/Q6b76XQQN00
4 - Homochirality: https://youtu.be/tqbpd3CmBgE
5 - Carbohydrates: https://youtu.be/rdqd_EvpsZM
6 - Building Blocks of Building Blocks: https://youtu.be/CCf-OfFpS_k
7 - Peptides: https://youtu.be/0Hv6KjB0j8Y
8 - Nucleotides: https://youtu.be/CYiguQYCSio
9 - Intermediate Summary & a Call to Colleagues: https://youtu.be/ImPxfmKrmoY
10 - Lipids: https://youtu.be/QTQd5Ifqv2g
11 - Chiral-induced Spin Selectivity: https://youtu.be/VKEZSfuMgL0
12.1 - Cell Construction & The Assembly Problem, Part 1: https://youtu.be/IaJo5jWs_6k
12.2 - Cell Construction & The Assembly Problem, Part 2: https://youtu.be/fDayvhch_W4
13 - Summary & Projections: https://youtu.be/71GTCHkId6M

Link to the cited video ("Elucidating the Agenda of James Tour: A Defense of Abiogenesis") can be found in the video description of Episode 0 - "Reasons for this Series" here: https://youtu.be/71dqAFUb-v0

The passionate thumbnail for this video uses a still frame image taken from Dr. Tour's video on Flash Graphene when he says "any" in the phrase "any carbon source" at 0:12: https://youtu.be/hhN5I_ocLSU

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God bless you.

#Abiogenesis #JamesTour #OriginOfLife

~
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