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肥胖 削弱疫苗效力
3 years ago
2
2022年5月7日
世界衛生組織(WHO)先前曾表示:歐洲有近60%成年人及1/3的兒童屬於肥胖症或超重,甚至形容情況已經達成「流行病」的程度。在新冠肺炎疫情流行當下,肥胖甚至會影響到疫苗的效力,土耳其近來有一項研究指出,嚴重肥胖可能會削弱新冠肺炎疫苗對從未感染者的保護力。
根據《路透社》報導:近來土耳其進行了一項小型研究,該研究中比較了124名身體質量指數(BMI)高於40的嚴重肥胖患者以及166名BMI小於25的正常體重者對於疫苗的免疫反應,讓其中130名受試者接種2劑輝瑞BNT疫苗,另外160名受試者則是接種2劑科興疫苗。
研究結果顯示:在已接種2劑輝瑞BNT疫苗,但從未感染新冠的受試者中,嚴重肥胖者的抗體水平比正常體重者低了3倍以上,而其餘沒有感染史,且接種2劑科興疫苗的人,嚴重肥胖者的抗體水平也比正常體重者低27倍。
相比之下,參與這項研究的70名曾感染過新冠肺炎的人當中,不管是否嚴重肥胖,抗體水平相似。
研究作者者沃爾坎(Volkan Demirhan Yumuk)表示:雖然接種2劑輝瑞BNT疫苗的嚴重肥胖者產生比科興疫苗更多的抗體,但由於他們的抗體明顯比正常體重者來得低,因此需進一步研究,以確定這些更高的抗體水平是否能更有效的預防新冠肺炎。
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