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mRNA vaccines are experiencing a burst in basic research and preclinical/clinical trials. Multiple mRNA vaccine platforms against infectious diseases and several types of cancer have demonstrated encouraging results in both animal models and humans. https://integraterna.creative-biogene.com/application/mrna-vaccines.html

Creative Biogene provides reagents, kits, and services that help researchers explore questions about gene discovery, regulation, and function. Creative Biogene holds a leadership position in the global market and is committed to improving the human condition through biotechnology. https://qvirus.creative-biogene.com/

Creative Biogene, a global provider and manufacturer, offers professional products and services to help our clients in gene research. CRISPR/Cas9 PlatformCB, which provides comprehensive gene editing services and products by using CRISPR/Cas9 technology, is one of Creative Biogene’s platforms.

Creative Bioarray is offering Caco-2 permeability assay to help determine the absorption and the bioavailability of drug candidates, facilitating the lead optimization process in drug discovery. https://www.creative-bioarray.com/Services/caco-2-permeability-assay.htm

Creative Bioarray specializes in predictive, 3D tissue and cell-based in vitro toxicity assays using primary cells from many different tissues and organs. We know how keeping control of time and costs is valuable to our clients. https://dda.creative-bioarray.com/in-vitro-toxicology.html

Creative Bioarray is a reliable Parallel Artificial Membrane Permeability Assay (PAMPA) provider. Over the past years, Creative Bioarray has developed expertise in PAMPA. By working with a variety of customers, we can perfectly meet your project requirements and budgets. https://www.creative-bioarray.com/Services/pampa-assay.htm

Oncolytic viruses (OVs) are a class of viruses that can selectively replicate in and lyse cancer cells, and subsequent spread with a tumor while not causing damage to normal cells. Besides the direct oncolytic activity, OVs are also effective in stimulating the body immune responses which can further help recogonize, control or destroy cancer cells. Through the combination of the tumor-specific cell lysis and immune stimulation, OVs act their antitumor activities in situ. https://www.creative-biogene.com/products/oncolytic-virus.html

Creative Biogene provides world-class packaging services for a variety of viral types using our QVirusTM platform. Creative Biogene's state-of-the-art facilities and highly experienced staff are available in order to assist in all areas of virus vector design and construction, as well as the generation of the virus in a quick turnaround. https://www.creative-biogene.com/Services/Custom-Viral-Service

Creative Biogene CRISPR/Cas9 Platform brings a vast range of CRISPR-Cas9 services and products to clients. With years of experience and steady platform, our scientist team is expert in applications of CRISPR-Cas9 system. We offer various CRISPR-Cas9 related services and products to assist you for genome editing at various stages. We are dedicated to providing the most comprehensive, affordable and high-quality CRISPR-Cas9 related services and products to win your satisfaction in a professional manner. https://www.creative-biogene.com/crispr-cas9/service.html

Creative Biogene’s advanced technologies and highly experienced staffs are available to provide you a range of cDNA libraries construction service, including standard cDNA library, subtractive cDNA library, normalized cDNA library, full length cDNA library, yeast two-hybrid cDNA library and SSH cDNA library. Creative Biogene’s goal is to provide you with the most affordable and high-quality cDNA libraries construction service to ensure your satisfaction in a timely and professional manner. https://www.creative-biogene.com/Services/cDNA-Library-Construction-Service

Creative Biogene is the leading company offering the ABC (ATP binding cassette) transporters assays. With our abundant experience and expertise in transporters-based drug discovery, talented scientists in Creative Biogene are dedicating to providing the unmatched services to accelerate your research program and significantly increase your chance to success. https://www.creative-biogene.com/Services/Drug-Discovery-Services/ABC-transporters-Screening-and-Profilin-Assays.html

Creative Bioarray provides our global clients the most comprehensive histology services. Drawing on many years of experience and in-depth knowledge, Creative Bioarray offers tissue processing, embedding, sectioning, and staining. Besides a histological examination of all major organs/tissues is provided, including immunohistochemistry (IHC), immunofluorescence (IF), in situ hybridization (ISH), fluorescent in situ hybridization (FISH), and transmission electron mircoscopy.

Induced pluripotent stem (iPS) cells can be generated by somatic cell reprogramming following the exogenous expression of specific transcription factors (Oct-3/4, KLF4, SOX2, c-Myc, Nanog and Line28). These cell types are capable of unlimited, undifferentiated proliferation in vitro and still maintain the capacity to differentiated into a wide range of somatic cells. https://www.creative-bioarray.com/products/ipsc-differentiation-kit-list-207.htm

IHC, by exploiting the principle of antibodies binding specifically to antigens in biological tissues, is a routine method to detect antigens in cells of a tissue section. It is widely used in the diagnosis of diseases including cancer, neurological disease, digestive disease, etc. Specific molecular markers have been found and verified to be characteristic of particular cellular events in disease such as proliferation, apoptosis and inflammation. https://www.creative-bioarray.com/Services/Immunohistochemistry-IHC.htm

Cell cycle refers to the set of events through which a cell grows, replicates its genome, and ultimately divides into two daughter cells through the process of mitosis. Because the amount of DNA in a cell shows characteristic changes throughout the cycle, techniques known as cell cycle analysis can be used to separate a population of cells according to the different phases of cell cycle they are in, based on their varying DNA content.

Caco-2 permeability assay is one of the recommended in vitro methods in the United States FDA guidelines to evaluate drug permeability. It has become the gold standard method to evaluate both the passive and active transport and the absorption of orally administered drugs. The method can be used to assess the bidirectional permeability of a test compound (from the apical to the basolateral side or vice versa). By measuring the transport rate of a compound across a Caco-2 cell monolayer membrane, the in vivo absorption of the compound across the gut wall can be well predicted. https://www.creative-bioarray.com/Services/caco-2-permeability-assay.htm

Using a labeled complementary DNA, RNA or modified nucleic acids strand (i.e., probe), In Situ Hybridization (ISH) refers to localize a specific DNA or RNA sequence in a portion or section of tissue. This is a crucial step for understanding the organization, regulation, and function of genes. Another important histology technique of localization is immunohistochemistry; however, immunohistochemistry stains proteins instead of DNA or RNAs. https://www.creative-bioarray.com/Services/In-Situ-Hybridization-ISH.htm

The process of cell proliferation and differentiation plays a key role from the time of embryogenesis to development of whole organism from single- or double- cell embryo and continues its critical role in maintenance of adult tissue homoeostasis by recycling the old cells with new cells.

The CRISPR/Cas9 system is an adaptive immunity system in bacteria against bacteriophage invading. It has been developed as the most popular method for genome editing in recent years. https://www.creative-biogene.com/Product/Gene-Knockout-Stable-Cell-Lines.html

Tissue microarray is a high-throughput technique that allows rapid gene expression and copy-number surveys of large numbers of different tissue specimens. https://www.creative-bioarray.com/products/custom-tissue-array-189.htm

Fibroblast is a type of cell that synthesizes extracellular matrix and collagen, which form the basic framework structure of biological connective tissue in animals and play an important role in tissue repair. As well as being present as fibroblasts, these cells exist in an alternative state, as fibrocytes. Fibroblast is the term used to describe these cells when they are in an activated state. https://www.creative-bioarray.com/filter/fibroblast-cell-and-media-12.html

There are several biomarkers can be used to determine pluripotency of iPS cells. QualiStem® Human iPSC Characterization Kit (Flow Cytometry) from Creative Bioarray provides a quantitative solution for clearly identifying human iPS cells cultures using flow cytometry. The conjugated antibodies to phenotypically characterize human iPSCs, which were carefully selected to monitor and characterize human iPSCs cultures. https://www.creative-bioarray.com/qualistem-human-ipsc-characterization-kit-flow-cytometry-cat-csk-id005-item-5208.htm

miRNAs play important roles in various cellular processes including apoptosis, cell division, and proliferation and others. Investigations of miRNAs will help to decipher protein functions and even discover new drugs. Creative Biogene is committed to providing outstanding miRNA products and comprehensive services to facilitate and simplify miRNA investigation. https://www.creative-biogene.com/Services/MicroRNA-Agomir-Antagomir-Synthesis-Service.html

Cells are structural and functional unit of our body which control and maintain the function of all unicellular and multicellular organisms. The process of cell proliferation and differentiation plays a key role from the time of embryogenesis to development of whole organism from single- or double- cell embryo and continues its critical role in maintenance of adult tissue homoeostasis by recycling the old cells with new cells. https://www.creative-bioarray.com/Services/cell-proliferation-assay-services.htm

Adult stem cells are undifferentiated cells, found throughout the body after development that multiply by cell division to replenish dying cells and regenerate damaged tissues. Also known as somatic stem cells, they can be found in juvenile as well as adult animals and human bodies. Creative Bioarray provides adult stem cells from various tissue/organs of human, mouse and rat. https://www.creative-bioarray.com/products/adult-stem-cells-34.htm